Description

(S)-1-(5-Nitropyridine-2-Yl)Pyrrolidine-3-Ol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its defined stereochemistry and functionalized heterocyclic structure make it a valuable synthon for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for advanced synthesis projects.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its nitropyridine moiety.
• Ligand Synthesis: Serves as a starting material for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and enzyme inhibition.
• Fine Chemical Production: Utilized in multi-step synthetic routes for producing complex, high-value specialty chemicals.

Basic Information

Product Name	(S)-1-(5-Nitropyridine-2-Yl)Pyrrolidine-3-Ol
CAS No.	1233859-93-2
Molecular Formula	C9H11N3O3
Molecular Weight	209.20 g/mol
Synonyms	(S)-3-Hydroxy-1-(5-nitropyridin-2-yl)pyrrolidine; (S)-1-(5-Nitro-2-pyridinyl)-3-pyrrolidinol; (S)-1-(5-Nitropyridin-2-yl)pyrrolidin-3-ol; (S)-1-(5-Nitro-2-pyridyl)pyrrolidine-3-ol; (S)-Pyrrolidin-3-ol, 1-(5-nitropyridin-2-yl)-; 1233859-93-2; (S)-enantiomer of 1-(5-Nitropyridin-2-yl)pyrrolidin-3-ol
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Nitropyridine-2-Yl)Pyrrolidine-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.