Description

3-Fluoro-5-Nitropyridin-2-Amine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Serves as a versatile precursor for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its electron-deficient pyridine core.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-5-Nitropyridin-2-Amine
CAS No.	1232432-08-4
Molecular Formula	C5H4FN3O2
Molecular Weight	157.10 g/mol
Synonyms	2-Amino-3-fluoro-5-nitropyridine; 3-Fluoro-5-nitro-2-pyridinamine; 5-Nitro-3-fluoropyridin-2-amine; 2-Pyridinamine, 3-fluoro-5-nitro-; 3-Fluoro-5-nitropyridin-2-ylamine; 3-Fluoro-5-nitro-2-aminopyridine; 3-Fluoro-5-nitropyridine-2-amine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Nitropyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.