Description

Ly-2784544 (Hcl) is a high-purity small molecule compound, specifically the hydrochloride salt form of a selective kinase inhibitor. This compound is critical for pharmaceutical research and development, particularly in the study of targeted cancer therapies. It is primarily utilized by research scientists and process development chemists in the biotechnology and pharmaceutical industries for preclinical studies, assay development, and as a reference standard.

Application

• Pharmaceutical R&D Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery pipelines.
• Biochemical Assay Reagent: Serves as a key inhibitor in enzymatic and cellular assays to study specific kinase pathways and their role in disease mechanisms.
• Preclinical In Vitro Studies: Employed in cell-based experiments to evaluate potency, selectivity, and efficacy in relevant disease models.
• Process Chemistry & Formulation: Acts as an intermediate or starting material for salt selection studies, formulation development, and stability testing.
• Academic Research: Utilized in university and institutional labs for fundamental research in oncology, signal transduction, and medicinal chemistry.

Basic Information

Product Name	Ly-2784544 (Hcl)
CAS No.	1229236-87-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LY2784544 hydrochloride; 4-(4-Methylpiperazin-1-ylmethyl)-N-[4-methyl-3-[(4-pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide hydrochloride; GANDOSINIB hydrochloride; LY 2784544 HCl; 4-(4-Methyl-1-piperazinyl)methyl-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide monohydrochloride
EINECS	Contact for details

Quality Control

Our Ly-2784544 (Hcl) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A detailed Certificate of Analysis (COA) documenting identity, purity, and strength is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.