Description

Benzyl 3-(Benzyloxycarbonylamino)Pyridine-2-Carboxylate is a high-purity, protected amino acid derivative, specifically a pyridine-based building block, essential for advanced organic synthesis. Its primary value lies in serving as a key, versatile intermediate for constructing complex molecules in pharmaceutical research and development. This compound is critically needed by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), particularly in the areas of kinase inhibitors and other nitrogen-containing heterocycles. Its protected functional groups allow for selective reactions, streamlining multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Peptidomimetic Synthesis: Serves as a constrained, non-natural amino acid analog for creating peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Benzyl 3-(Benzyloxycarbonylamino)Pyridine-2-Carboxylate
CAS No.	1228956-95-3
Molecular Formula	C21H18N2O4
Molecular Weight	362.38 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, phenylmethyl ester; Benzyl 3-((benzyloxy)carbonylamino)picolinate; 3-(N-Cbz-amino)picolinic acid benzyl ester; Cbz-3-Aminopicolinic Acid Benzyl Ester; Z-3-Aminopicolinic Acid Bn Ester; 3-[(Benzyloxycarbonyl)amino]pyridine-2-carboxylic acid benzyl ester; (Benzyloxycarbonylamino)pyridinecarboxylate benzyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 3-(Benzyloxycarbonylamino)Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.