Description

1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine dihydrochloride is a high-purity, heterocyclic organic compound with the CAS number 1228878-69-0. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other bioactive molecules.

Application

This specialized chemical building block serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial scaffold in the research and synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the multi-step synthesis of potential APIs.
• Biochemical Research: Employed as a tool compound in biochemical assays and for probing biological pathways.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine dihydrochloride
CAS No.	1228878-69-0
Molecular Formula	C8H14Cl2N3
Molecular Weight	223.12 g/mol
Synonyms	1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine hydrochloride (1:2); 1-Methyl-1,4,5,6,7,8-hexahydropyrazolo[3,4-c]pyridine dihydrochloride; 1-Methyl-4,5,6,7-tetrahydro-pyrazolo[3,4-c]pyridine dihydrochloride; 1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine HCl; 1228878-69-0; 1-Methyl-1,4,5,6,7,8-hexahydro-pyrazolo[3,4-c]pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.