Description

1-(2,3-Difluorophenyl)Ethanol is a versatile fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which can dramatically alter the electronic properties, metabolic stability, and bioavailability of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where fluorine substitution enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving thermal stability and optical properties.
• Advanced Polymer Chemistry: Incorporated as a monomer or chain modifier to create specialty polymers with unique solubility and surface characteristics.
• Catalyst & Ligand Development: Employed in the design of novel chiral ligands for asymmetric catalysis, leveraging the fluorine atoms for fine-tuning steric and electronic effects.
• Chemical Research & Development: A valuable standard and starting material for method development and exploring new fluorination chemistry pathways in academic and industrial labs.

Basic Information

Product Name	1-(2,3-Difluorophenyl)Ethanol
CAS No.	1228690-56-9
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	2,3-Difluoro-α-methylbenzyl alcohol; (2,3-Difluorophenyl)methylcarbinol; 1-(2,3-Difluorophenyl)ethan-1-ol; α-Methyl-2,3-difluorobenzyl alcohol; 2,3-Difluoro-α-methylbenzenemethanol; 1-(2,3-Difluorophenyl)-1-ethanol; (RS)-1-(2,3-Difluorophenyl)ethanol
EINECS	Contact for details

Quality Control

Our 1-(2,3-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.