Description

(E)-1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carbaldehyde Oxime is a high-purity, advanced pharmaceutical intermediate characterized by its specific oxime and pivaloyl functional groups. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex heterocyclic molecules. It is primarily sought by research organizations and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas requiring sophisticated nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• API Development: Serves as a key chiral or functionalized building block for constructing complex molecules in preclinical and process development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of proprietary compounds.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	(E)-1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carbaldehyde Oxime
CAS No.	1228670-57-2
Molecular Formula	C14H17N3O3
Molecular Weight	275.31 g/mol
Synonyms	(E)-1-Pivaloyl-1,2,3,4-tetrahydropyrido[2,3-b][1,4]oxazine-6-carbaldehyde oxime; 1,2,3,4-Tetrahydropyrido[2,3-b][1,4]oxazine-6-carboxaldehyde, 1-(2,2-dimethyl-1-oxopropoxy)-, oxime; 1-(2,2-Dimethylpropanoyl)-3,4-dihydro-2H-pyrido[2,3-b][1,4]oxazine-6-carbaldehyde oxime; (E)-1-(2,2-Dimethylpropanoyl)-3,4-dihydro-2H-pyrido[2,3-b][1,4]oxazine-6-carbaldehyde oxime; 1228670-57-2; Pyrido[2,3-b][1,4]oxazine-6-carbaldehyde oxime derivative
EINECS	Contact for details

Quality Control

Our (E)-1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carbaldehyde Oxime is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.