Description

(E)-Methyl 3-(2-Methoxy-6-(Pyrrolidin-1-Yl)-Pyridin-3-Yl)Acrylate is a high-value, functionalized acrylate ester and a key synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring a pyrrolidinyl-substituted pyridine core, makes it a versatile building block for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its heterocyclic amine functionality.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where its structural motifs can contribute to biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers and coatings with tailored properties.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex organic molecules via reactions like Michael additions or cyclizations.
• Ligand & Catalyst Development: The pyridine and pyrrolidine groups make it a useful scaffold for designing novel ligands in coordination chemistry and catalysis.

Basic Information

Product Name	(E)-Methyl 3-(2-Methoxy-6-(Pyrrolidin-1-Yl)-Pyridin-3-Yl)Acrylate
CAS No.	1228670-27-6
Molecular Formula	C15H20N2O3
Molecular Weight	276.33 g/mol
Synonyms	Methyl (2E)-3-[2-methoxy-6-(pyrrolidin-1-yl)-3-pyridyl]prop-2-enoate; Methyl (E)-3-(2-Methoxy-6-(1-Pyrrolidinyl)-3-Pyridinyl)Acrylate; 2-Propenoic acid, 3-[2-methoxy-6-(1-pyrrolidinyl)-3-pyridinyl]-, methyl ester, (2E)-; (E)-Methyl 3-(2-methoxy-6-(pyrrolidin-1-yl)pyridin-3-yl)acrylate; Methyl 3-(2-Methoxy-6-(Pyrrolidin-1-Yl)-Pyridin-3-Yl)Acrylate (E-isomer)
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(2-Methoxy-6-(Pyrrolidin-1-Yl)-Pyridin-3-Yl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.