Description

7-Iodo-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting complex diseases. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, especially in kinase inhibitor and CNS-targeted therapeutic research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile iodine handle for cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Material Science: Potential monomer or precursor for functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Useful as a probe or tag in bioconjugation and labeling applications.
• Academic & Contract Research: Employed in synthetic methodology development and as a reference standard in analytical laboratories.

Basic Information

Product Name	7-Iodo-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine
CAS No.	1228666-55-4
Molecular Formula	C9H8INO2
Molecular Weight	289.07 g/mol
Synonyms	7-Iodo-2,3-dihydro[1,4]dioxino[2,3-b]pyridine; [1,4]Dioxino[2,3-b]pyridine, 7-iodo-2,3-dihydro-; 2,3-Dihydro-7-iodo-[1,4]dioxino[2,3-b]pyridine; 7-Iodo-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; 7-Iodo-2,3-dihydro-1,4-dioxino[2,3-b]pyridine (CAS 1228666-55-4); 7-Iodo-2,3-dihydro[1,4]dioxino[2,3-b]pyridine; 7-Iodo-2,3-dihydro[1,4]dioxino[2,3-b]pyridine, 95+%; 7-Iodo-2,3-dihydro-1,4-dioxino[2,3-b]pyridine, 95+%
EINECS	Contact for details

Quality Control

Our 7-Iodo-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.