Description

2-Fluoro-n-Methoxy-n-Methyl-6-(Pyrrolidin-1-Yl)-Nicotinamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop next-generation drug candidates with enhanced efficacy and selectivity profiles.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules.
• Biochemical Tool Compound: Potential use in developing enzyme inhibitors or receptor modulators for biological research.
• Fine Chemical Synthesis: Serves as a precursor for other specialty chemicals requiring its specific fluorinated nicotinamide scaffold.

Basic Information

Product Name	2-Fluoro-n-Methoxy-n-Methyl-6-(Pyrrolidin-1-Yl)-Nicotinamide
CAS No.	1228666-39-4
Molecular Formula	C13H18FN3O2
Molecular Weight	267.30 g/mol
Synonyms	2-Fluoro-N-methoxy-N-methyl-6-(pyrrolidin-1-yl)nicotinamide; 6-(1-Pyrrolidinyl)-2-fluoro-N-methoxy-N-methyl-3-pyridinecarboxamide; 2-Fluoro-6-(pyrrolidin-1-yl)-N-methoxy-N-methylnicotinamide; 1228666-39-4; UNII-8H8P3L3Q8K; 8H8P3L3Q8K; Nicotinamide, 2-fluoro-N-methoxy-N-methyl-6-(1-pyrrolidinyl)-; SCHEMBL21845427
EINECS	Contact for details

Quality Control

Our 2-Fluoro-n-Methoxy-n-Methyl-6-(Pyrrolidin-1-Yl)-Nicotinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques like HPLC, GC, NMR, and MS. We are committed to meeting the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.