Description

5-Bromo-2-Chloro-6-Phenylpyridine-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring bromo, chloro, phenyl, and cyano substituents on a pyridine core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a critical precursor for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Development: Used as a building block for creating new herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex molecular fragments.
• Academic & Contract Research: Essential for methodological studies and library synthesis in academic institutions and contract research organizations (CROs).

Basic Information

Product Name	5-Bromo-2-Chloro-6-Phenylpyridine-3-Carbonitrile
CAS No.	1228182-75-9
Molecular Formula	C12H6BrClN2
Molecular Weight	293.55 g/mol
Synonyms	5-Bromo-2-chloro-6-phenylnicotinonitrile; 3-Cyano-5-bromo-2-chloro-6-phenylpyridine; 2-Chloro-5-bromo-6-phenylpyridine-3-carbonitrile; 5-Bromo-2-chloro-6-phenyl-3-pyridinecarbonitrile; 1228182-75-9; 5-Br-2-Cl-6-Ph-Py-3-CN
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-6-Phenylpyridine-3-Carbonitrile is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates, ensuring traceability and compliance for global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.