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1-(Morpholine-4-Sulfonyl)-Piperidin-4-Ylamine Hydrochloride CAS NO 1228070-80-1


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CAS No.:1228070-80-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(Morpholine-4-Sulfonyl)-Piperidin-4-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct sulfonamide-piperidine core structure. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

  • Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for oncology and central nervous system (CNS) targets.
  • Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
  • Kinase Inhibitor Synthesis: Serves as a core structural component in the design and synthesis of potential protein kinase inhibitors.
  • Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name 1-(Morpholine-4-Sulfonyl)-Piperidin-4-Ylamine Hydrochloride
CAS No. 1228070-80-1
Molecular Formula C9H20ClN3O3S
Molecular Weight 285.79 g/mol
Synonyms 4-Amino-1-(morpholine-4-sulfonyl)piperidine hydrochloride; 1-(4-Morpholinesulfonyl)-4-piperidinamine hydrochloride; 4-Piperidinamine, 1-(4-morpholinylsulfonyl)-, hydrochloride; Piperidin-4-ylamine, 1-(morpholine-4-sulfonyl)-, hydrochloride; 1-Morpholinosulfonylpiperidin-4-amine HCl
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Quality Control

Our 1-(Morpholine-4-Sulfonyl)-Piperidin-4-Ylamine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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