Description

2-(4-Amino-2,6-Dichlorophenoxy)-3-(Trifluoromethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture combining pyridine, phenoxy, and trifluoromethyl groups. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. Industrial and research chemists in the pharmaceutical, agrochemical, and specialty chemical sectors need this precise intermediate to develop next-generation compounds with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology and central nervous system (CNS) therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging its halogenated and fluorinated structure for improved biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and ligands for catalytic systems due to its stable aromatic and amino functionalities.

Basic Information

Product Name	2-(4-Amino-2,6-Dichlorophenoxy)-3-(Trifluoromethyl)Pyridine
CAS No.	1227955-22-7
Molecular Formula	C13H7Cl2F3N2O
Molecular Weight	335.11 g/mol
Synonyms	2-(4-Amino-2,6-dichlorophenoxy)-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-2-[4-amino-2,6-dichlorophenoxy]pyridine; 2,6-Dichloro-4-[(3-trifluoromethyl-2-pyridinyl)oxy]aniline; 4-Amino-2,6-dichlorophenyl 3-(trifluoromethyl)pyridin-2-yl ether; CAS 1227955-22-7
EINECS	Contact for details

Quality Control

Our production of 2-(4-Amino-2,6-Dichlorophenoxy)-3-(Trifluoromethyl)Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. The material is manufactured under a quality system compliant with cGMP principles for pharmaceutical intermediates. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.