Description

3-Chloro-2-Methoxypyridin-4-Ol CAS NO 1227600-52-3 is a versatile pyridine derivative, a key heterocyclic building block in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with high precision and functionality. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, including herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-rich pyridine structure.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Item	Detail
Product Name	3-Chloro-2-Methoxypyridin-4-Ol
CAS No.	1227600-52-3
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	4-Hydroxy-3-chloro-2-methoxypyridine; 3-Chloro-2-methoxy-4-pyridinol; 2-Methoxy-3-chloro-4-hydroxypyridine; 3-Chloro-2-methoxypyridin-4-ol; 4-Pyridinol, 3-chloro-2-methoxy-; 1227600-52-3; 3-Chloro-2-methoxypyridin-4-ol (Main)
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Methoxypyridin-4-Ol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.