Description

2,3-Diiodo-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, prized for its unique reactivity profile. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, antiviral agents, and oncology treatments.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl and diiodo groups contribute to biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a sophisticated building block for creating specialized ligands used in transition metal catalysis, enabling challenging cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated polymers, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create tagged molecules or photoaffinity labels for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2,3-Diiodo-5-(Trifluoromethyl)Pyridine
CAS No.	1227599-67-8
Molecular Formula	C6H2F3I2N
Molecular Weight	398.89 g/mol
Synonyms	5-(Trifluoromethyl)-2,3-diiodopyridine; 2,3-Diiodo-5-trifluoromethylpyridine; Pyridine, 2,3-diiodo-5-(trifluoromethyl)-; 2,3-Diiodo-5-(trifluoromethyl)pyridine; 2,3-Diiodo-5-(trifluoromethyl)pyridine (CAS 1227599-67-8); 5-Trifluoromethyl-2,3-diiodopyridine; 2,3-Diiodo-5-(trifluoromethyl)pyridine, 97%
EINECS	Contact for details

Quality Control

Our 2,3-Diiodo-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.