Description

2-Bromo-4-Fluoro-3-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used to create advanced herbicides and pesticides with improved efficacy and selectivity.
• Material Science Research: Serves as a monomer or functionalizing agent for developing specialty polymers and liquid crystals.
• Chemical Biology: Employed as a probe or labeling reagent in bioconjugation and target identification studies.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	2-Bromo-4-Fluoro-3-Methylpyridine
CAS No.	1227599-65-6
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Bromo-4-fluoro-3-picoline; 3-Methyl-2-bromo-4-fluoropyridine; 4-Fluoro-3-methyl-2-bromopyridine; 2-Bromo-4-fluoro-3-methylpyridine; 1227599-65-6; 3-Picoline, 2-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-3-Methylpyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.