Description

(3-Bromo-5-Chloropyridin-2-Yl)Methanol is a high-purity, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science Research: Intermediate for synthesizing functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.
• Academic and Industrial Research: Utilized in medicinal chemistry and chemical biology for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	(3-Bromo-5-Chloropyridin-2-Yl)Methanol
CAS No.	1227599-26-9
Molecular Formula	C6H5BrClNO
Molecular Weight	222.47 g/mol
Synonyms	2-(Hydroxymethyl)-3-bromo-5-chloropyridine; (3-Bromo-5-chloro-2-pyridinyl)methanol; 3-Bromo-5-chloropyridine-2-methanol; 5-Chloro-3-bromo-2-pyridinemethanol; 2-Pyridinemethanol, 3-bromo-5-chloro-; (3-Bromo-5-chloro-pyridin-2-yl)-methanol
EINECS	Contact for details

Quality Control

Every batch of (3-Bromo-5-Chloropyridin-2-Yl)Methanol is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) are provided with each shipment, and we support custom synthesis to meet specific purity requirements (e.g., ≥98%, ≥99%) for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.