Description

5-Bromo-6-Fluoropyridin-2-Ol is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated heterocycles.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the design of novel chelating ligands for transition metal catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic agents due to its modifiable functional groups.

Basic Information

Product Name	5-Bromo-6-Fluoropyridin-2-Ol
CAS No.	1227597-58-1
Molecular Formula	C5H3BrFNO
Molecular Weight	191.99 g/mol
Synonyms	2-Hydroxy-5-bromo-6-fluoropyridine; 5-Bromo-6-fluoro-2-pyridinol; 5-Bromo-6-fluoro-2-hydroxypyridine; 6-Fluoro-5-bromopyridin-2-ol; 2-Pyridinol, 5-bromo-6-fluoro-; 5-Bromo-6-fluoro-2(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoropyridin-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.