Description

5-Fluoro-6-Methylpyridin-2(1H)-One is a high-value fluorinated pyridinone derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and a lactam moiety, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of specialized ligands for catalysis or functional organic materials.
• Chemical Biology Probe: Serves as a core structure for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	5-Fluoro-6-Methylpyridin-2(1H)-One
CAS No.	1227594-46-8
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	5-Fluoro-6-methyl-1,2-dihydropyridin-2-one; 5-Fluoro-6-methyl-2-hydroxypyridine; 5-Fluoro-6-methylpyridin-2-ol; 2-Hydroxy-5-fluoro-6-methylpyridine; 6-Methyl-5-fluoropyridin-2(1H)-one; 5-Fluoro-6-methyl-2(1H)-pyridinone
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methylpyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.