Description

2-Bromo-3-Methoxy-5-Trifluoromethylpyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and trifluoromethylated structure makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and labeling reagents for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Bromo-3-Methoxy-5-Trifluoromethylpyridine
CAS No.	1227594-04-8
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	5-(Trifluoromethyl)-3-methoxy-2-bromopyridine; 2-Bromo-3-methoxy-5-(trifluoromethyl)pyridine; 3-Methoxy-2-bromo-5-trifluoromethylpyridine; Pyridine, 2-bromo-3-methoxy-5-(trifluoromethyl)-; 1227594-04-8
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Methoxy-5-Trifluoromethylpyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.