Description

2-Chloro-6-(Trifluoromethyl)Pyridine-3-Acetic Acid is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating compounds with enhanced biological activity and specific physical properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	2-Chloro-6-(Trifluoromethyl)Pyridine-3-Acetic Acid
CAS No.	1227592-95-1
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	2-Chloro-6-(trifluoromethyl)nicotinic acid, methylene homologue; 3-Pyridineacetic acid, 2-chloro-6-(trifluoromethyl)-; 2-Chloro-6-trifluoromethylpyridine-3-acetic acid; α-Carboxy-2-chloro-6-trifluoromethylpyridine; (2-Chloro-6-(trifluoromethyl)pyridin-3-yl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(Trifluoromethyl)Pyridine-3-Acetic Acid is manufactured and tested under a strict quality management system. We guarantee high purity and consistent quality suitable for demanding research and scale-up applications. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.