Description

4-Bromo-2-Fluoro-6-Methoxypyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists developing active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for bioactivity.
• Ligand and Catalyst Development: Used to create sophisticated pyridine-based ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Intermediate in the synthesis of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic and R&D: Utilized in research laboratories for method development and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-Methoxypyridine
CAS No.	1227591-12-9
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	2-Fluoro-6-methoxy-4-bromopyridine; 4-Bromo-2-fluoro-6-methoxypyridine; 6-Methoxy-4-bromo-2-fluoropyridine; Pyridine, 4-bromo-2-fluoro-6-methoxy-; 1227591-12-9; 4-Br-2-F-6-MeO-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoro-6-Methoxypyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.