Description

2-Chloro-3-Trifluoromethylisonicotinic Acid is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, offering a unique trifluoromethylated pyridine scaffold. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand & Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic processes.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Essential for fine chemical companies offering bespoke synthesis services for client-specific molecules.

Basic Information

Product Name	2-Chloro-3-Trifluoromethylisonicotinic Acid
CAS No.	1227587-24-7
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	2-Chloro-3-(trifluoromethyl)isonicotinic Acid; 2-Chloro-3-(trifluoromethyl)pyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 2-chloro-3-(trifluoromethyl)-; 2-Chloro-3-trifluoromethyl-4-pyridinecarboxylic Acid; 2-Chloro-3-trifluoromethylpyridine-4-carboxylic Acid; 2-Chloro-3-(trifluoromethyl)-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Trifluoromethylisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets stringent specifications for research and commercial use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.