Description

3-Bromo-6-(Trifluoromethyl)Pyridine-2-Methanol is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical candidates and agrochemicals, where its unique structure enables the introduction of key pharmacophores. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke synthesis projects requiring a specific, high-purity brominated pyridine derivative.

Basic Information

Product Name	3-Bromo-6-(Trifluoromethyl)Pyridine-2-Methanol
CAS No.	1227586-09-5
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	2-(Hydroxymethyl)-3-bromo-6-(trifluoromethyl)pyridine; (3-Bromo-6-(trifluoromethyl)pyridin-2-yl)methanol; 3-Bromo-6-(trifluoromethyl)-2-pyridinemethanol; 2-Pyridinemethanol, 3-bromo-6-(trifluoromethyl)-; 3-Bromo-6-trifluoromethyl-pyridine-2-methanol
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(Trifluoromethyl)Pyridine-2-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.