Description

2-Bromomethyl-3-Fluoro-5-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring bromomethyl, fluoro, and trifluoromethyl substituents, makes it an essential intermediate for introducing specific functionalities into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials and liquid crystals due to its unique electronic properties imparted by the halogen atoms.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromomethyl-3-Fluoro-5-(Trifluoromethyl)Pyridine
CAS No.	1227583-97-2
Molecular Formula	C8H4BrF4N
Molecular Weight	270.02 g/mol
Synonyms	3-Fluoro-5-(trifluoromethyl)-2-(bromomethyl)pyridine; 2-(Bromomethyl)-3-fluoro-5-(trifluoromethyl)pyridine; Pyridine, 2-(bromomethyl)-3-fluoro-5-(trifluoromethyl)-; 2-Bromomethyl-3-fluoro-5-trifluoromethylpyridine; 3-Fluoro-2-bromomethyl-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromomethyl-3-Fluoro-5-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and impurity profile is supplied with each shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.