Description

Benzenemethanol, 5-Nitro-2-(Trifluoromethyl)- is a high-value, multifunctional aromatic building block characterized by its nitro and trifluoromethyl substituents. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds to impart specific electronic and steric properties into target molecules. It is primarily sought after by the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates in drug discovery and crop protection agent development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, contributing to the molecular framework of dyes and charge-transport layers.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in cross-coupling reactions and as a ligand precursor in catalytic systems.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	Benzenemethanol, 5-Nitro-2-(Trifluoromethyl)-
CAS No.	1227582-22-0
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	5-Nitro-2-(trifluoromethyl)benzyl alcohol; (5-Nitro-2-(trifluoromethyl)phenyl)methanol; 2-(Trifluoromethyl)-5-nitrobenzenemethanol; α-(5-Nitro-2-trifluoromethylphenyl)methanol; Benzenemethanol, 5-nitro-2-(trifluoromethyl)-; 5-Nitro-α,α,α-trifluoro-o-tolyl alcohol
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanol, 5-Nitro-2-(Trifluoromethyl)- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including purity by HPLC, identity confirmation by IR and NMR, and impurity profiling is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.