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2-Amino-3-Methoxy-4-(Trifluoromethyl)Pyridine CAS NO 1227581-88-5


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CAS No.:1227581-88-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-3-Methoxy-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its amino, methoxy, and trifluoromethyl substituents. This compound is essential for the synthesis of complex molecules, where its unique structure imparts desirable physicochemical properties such as enhanced metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
  • Material Science Research: Serves as a precursor for functionalized ligands in catalysis and for the development of specialty polymers and electronic materials.
  • Chemical Biology: Employed as a probe or labeling reagent in biochemical research due to its reactive amino group and fluorine tags.
  • Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis services catering to the needs of biotechnology and fine chemical companies.

Basic Information

Product Name 2-Amino-3-Methoxy-4-(Trifluoromethyl)Pyridine
CAS No. 1227581-88-5
Molecular Formula C7H7F3N2O
Molecular Weight 192.14 g/mol
Synonyms 4-(Trifluoromethyl)-3-methoxypyridin-2-amine; 3-Methoxy-4-trifluoromethyl-2-aminopyridine; 2-Pyridinamine, 3-methoxy-4-(trifluoromethyl)-; 2-Amino-3-methoxy-4-trifluoromethylpyridine; 4-Trifluoromethyl-3-methoxy-2-aminopyridine; 2-Amino-3-methoxy-4-(trifluoromethyl)pyridine; 3-Methoxy-4-(trifluoromethyl)pyridin-2-amine
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Quality Control

Our 2-Amino-3-Methoxy-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC/IR) Conforms
Assay (HPLC) ≥98.0%
Related Substances (HPLC) Total impurities ≤2.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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