Description

4-Iodo-5-Methylpyridin-2-Amine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the introduction of both iodine and amine functionalities into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Used to create labeled compounds for studying biological pathways and mechanisms.

Basic Information

Product Name	4-Iodo-5-Methylpyridin-2-Amine
CAS No.	1227581-81-8
Molecular Formula	C6H7IN2
Molecular Weight	234.04 g/mol
Synonyms	2-Amino-4-iodo-5-methylpyridine; 5-Methyl-4-iodopyridin-2-amine; 4-Iodo-5-methyl-2-pyridinamine; 4-Iodo-5-methylpyridine-2-amine; 2-Pyridinamine, 4-iodo-5-methyl-
EINECS	Contact for details

Quality Control

Our 4-Iodo-5-Methylpyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.