Description

2-Amino-4-Chloro-5-(Trifluoromethyl)Pyridine is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and chloro-substituted structure makes it an invaluable intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Research & Development: Employed as a versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
• Ligand Synthesis: Useful for creating complex chelating agents and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Amino-4-Chloro-5-(Trifluoromethyl)Pyridine
CAS No.	1227581-65-8
Molecular Formula	C6H4ClF3N2
Molecular Weight	196.56 g/mol
Synonyms	4-Chloro-5-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 4-chloro-5-(trifluoromethyl)-; 4-Chloro-5-trifluoromethyl-2-aminopyridine; 2-Amino-4-chloro-5-trifluoromethylpyridine; 5-(Trifluoromethyl)-4-chloropyridin-2-amine; 4-Chloro-5-(trifluoromethyl)-2-aminopyridine; 2-Amino-4-chloro-alpha,alpha,α-trifluoro-5-picoline
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chloro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.