Description

2-Iodo-6-Methylpyridin-4-Ol CAS NO 1227580-33-7 is a halogenated pyridine derivative, a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a hydroxyl group on the pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the iodine atom facilitates further functionalization.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems due to its reactive handles.
• Custom Synthesis and Scale-up: A fundamental building block for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2-Iodo-6-Methylpyridin-4-Ol
CAS No.	1227580-33-7
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	4-Hydroxy-2-iodo-6-methylpyridine; 6-Methyl-2-iodopyridin-4-ol; 2-Iodo-6-methyl-4-pyridinol; 2-Iodo-6-methyl-4-hydroxypyridine; 4-Pyridinol, 2-iodo-6-methyl-; Iodomethylpyridinol
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-6-Methylpyridin-4-Ol is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.