Description

2-Fluoro-3-Hydroxy-5-(Trifluoromethyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and a trifluoromethyl group, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active molecule research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine and trifluoromethyl groups contribute to improved efficacy and environmental profile.
• Material Science Research: Acts as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-3-Hydroxy-5-(Trifluoromethyl)Pyridine
CAS No.	1227579-54-5
Molecular Formula	C6H3F4NO
Molecular Weight	181.09 g/mol
Synonyms	5-(Trifluoromethyl)-2-fluoro-3-pyridinol; 3-Hydroxy-2-fluoro-5-(trifluoromethyl)pyridine; 2-Fluoro-3-hydroxy-5-trifluoromethylpyridine; 2-Fluoro-5-(trifluoromethyl)pyridin-3-ol; 3-Pyridinol, 2-fluoro-5-(trifluoromethyl)-; 1227579-54-5
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Hydroxy-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.