Description

4-Bromo-5-Methylpyridin-2(1H)-One is a high-value brominated pyridone derivative, a crucial heterocyclic building block in advanced organic synthesis. Its unique structure makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands and catalysts used in metal-organic chemistry and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as novel charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for designing and synthesizing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Bromo-5-Methylpyridin-2(1H)-One
CAS No.	1227578-85-9
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	4-Bromo-5-methyl-1H-pyridin-2-one; 4-Bromo-5-methyl-2(1H)-pyridinone; 4-Bromo-5-methylpyridin-2-ol; 2-Hydroxy-4-bromo-5-methylpyridine; 5-Methyl-4-bromopyridin-2(1H)-one; 4-Bromo-5-methyl-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Methylpyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.