Description

2-Chloro-4-Fluoro-5-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of functional organic materials, such as liquid crystals and organic semiconductors, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Methylpyridine
CAS No.	1227574-24-4
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Chloro-4-fluoro-5-methylpyridine; 5-Methyl-2-chloro-4-fluoropyridine; 4-Fluoro-2-chloro-5-methylpyridine; 2-Chloro-4-fluoro-5-picoline; Pyridine, 2-chloro-4-fluoro-5-methyl-; 1227574-24-4
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluoro-5-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.