Description

6-Bromo-3-Chloropyridine-2-Methanol is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its bifunctional halogen and alcohol groups make it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its modifiable pyridine structure.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Fine Chemical Production: Acts as a building block for synthesizing complex dyes, flavors, and fragrances.

Basic Information

Product Name	6-Bromo-3-Chloropyridine-2-Methanol
CAS No.	1227563-68-9
Molecular Formula	C6H5BrClNO
Molecular Weight	222.47 g/mol
Synonyms	(6-Bromo-3-chloropyridin-2-yl)methanol; 2-(Hydroxymethyl)-6-bromo-3-chloropyridine; 3-Chloro-6-bromo-2-pyridinemethanol; 6-Bromo-3-chloro-2-pyridinemethanol; 6-Bromo-3-chloro-2-(hydroxymethyl)pyridine; 2-Pyridinemethanol, 6-bromo-3-chloro-; 6-Bromo-3-chloropyridine-2-ylmethanol
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloropyridine-2-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.