Description

(3-Bromo-5-(Trifluoromethyl)Pyridin-2-Yl)Methanol is a high-value pyridine derivative and a versatile building block in advanced organic synthesis. This compound matters for its unique trifluoromethyl and bromo substitution pattern, which is critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring specific halogenated aromatic units.
• Chemical Biology Probe: Useful for labeling and modifying biomolecules in drug discovery and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Item	Detail
Product Name	(3-Bromo-5-(Trifluoromethyl)Pyridin-2-Yl)Methanol
CAS No.	1227563-37-2
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	2-(Hydroxymethyl)-3-bromo-5-(trifluoromethyl)pyridine; [3-Bromo-5-(trifluoromethyl)-2-pyridinyl]methanol; 3-Bromo-5-(trifluoromethyl)pyridine-2-methanol; (3-Bromo-5-trifluoromethyl-pyridin-2-yl)-methanol; 2-Pyridinemethanol, 3-bromo-5-(trifluoromethyl)-; 3-Bromo-5-(trifluoromethyl)-2-pyridylmethanol
EINECS	Contact for details

Quality Control

Our (3-Bromo-5-(Trifluoromethyl)Pyridin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere for prolonged use to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.