Description

3-Chloro-2-(Chloromethyl)-5-Fluoropyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the introduction of both chloro and fluoromethyl functionalities into complex molecular architectures. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized pyridine-based ligands used in transition metal catalysis and material science applications.
• Chemical Research: Employed in academic and industrial R&D for exploring novel heterocyclic chemistry, fluorination methodologies, and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or organic electronic materials due to its halogenated pyridine core.

Basic Information

Product Name	3-Chloro-2-(Chloromethyl)-5-Fluoropyridine
CAS No.	1227563-19-0
Molecular Formula	C6H4Cl2FN
Molecular Weight	180.01 g/mol
Synonyms	2-(Chloromethyl)-3-chloro-5-fluoropyridine; 5-Fluoro-3-chloro-2-(chloromethyl)pyridine; 3-Chloro-5-fluoro-2-(chloromethyl)pyridine; 2-Chloromethyl-3-chloro-5-fluoropyridine; Pyridine, 3-chloro-2-(chloromethyl)-5-fluoro-; 1227563-19-0
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(Chloromethyl)-5-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.