Description

6-Bromo-5-Chloropicolinaldehyde is a high-purity halogenated picolinaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both bromo and chloro substituents adjacent to an aldehyde group, makes it an indispensable intermediate for constructing complex heterocyclic scaffolds. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands used in catalysis and material science.
• Heterocyclic Chemistry: Essential building block for constructing pyridine, pyrimidine, and other nitrogen-containing heterocycles of commercial interest.
• Material Science: Intermediate in the production of functionalized polymers and organic electronic materials.
• Chemical Biology: Used in the design and synthesis of molecular probes and bio-conjugation reagents.

Basic Information

Product Name	6-Bromo-5-Chloropicolinaldehyde
CAS No.	1227561-90-1
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	5-Chloro-6-bromopicolinaldehyde; 6-Bromo-5-chloro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 6-bromo-5-chloro-; 5-Chloro-6-bromo-2-formylpyridine; 6-Bromo-5-chloropyridine-2-carbaldehyde; 2-Formyl-5-chloro-6-bromopyridine; 6-Bromo-5-chloro-2-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloropicolinaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.