Description

3-Chloro-5-(Chloromethyl)-2-Methoxypyridine is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites—the chloromethyl and chloro substituents—which allow for selective functionalization and the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Chemical Synthesis: A versatile scaffold for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	3-Chloro-5-(Chloromethyl)-2-Methoxypyridine
CAS No.	1227516-74-6
Molecular Formula	C7H7Cl2NO
Molecular Weight	192.04 g/mol
Synonyms	2-Methoxy-3-chloro-5-(chloromethyl)pyridine; 5-(Chloromethyl)-3-chloro-2-methoxypyridine; 3-Chloro-2-methoxy-5-(chloromethyl)pyridine; 2-Methoxy-3,5-bis(chloromethyl)pyridine (incorrect but common search variant); Pyridine, 3-chloro-5-(chloromethyl)-2-methoxy-; CAS 1227516-74-6
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Chloromethyl)-2-Methoxypyridine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for prolonged storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.