Description

2-Amino-3-Chloro-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique trifluoromethyl and chloro-substituted structure makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Material Science Research: Employed as a precursor for synthesizing functionalized ligands, catalysts, and specialty polymers with tailored electronic properties.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Amino-3-Chloro-4-(Trifluoromethyl)Pyridine
CAS No.	1227513-97-4
Molecular Formula	C7H4ClF3N2
Molecular Weight	196.57 g/mol
Synonyms	2-Amino-3-chloro-4-(trifluoromethyl)pyridine; 3-Chloro-4-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 3-chloro-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-amino-3-chloropyridine; 3-Chloro-4-trifluoromethyl-2-aminopyridine; 2-Amino-3-chloro-4-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data with each shipment, including HPLC chromatograms and NMR spectra for identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is supplied and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.