Description

(2-Nitro-3-(Trifluoromethyl)Phenyl)Methanol is a high-value, multi-functional aromatic building block characterized by its nitro and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, offering a versatile handle for constructing complex molecules with tailored electronic and steric properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination methodologies and the unique properties imparted by the CF3 group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	(2-Nitro-3-(Trifluoromethyl)Phenyl)Methanol
CAS No.	1227511-82-1
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	[2-Nitro-3-(trifluoromethyl)phenyl]methanol; 2-Nitro-3-(trifluoromethyl)benzyl Alcohol; 1-(Hydroxymethyl)-2-nitro-3-(trifluoromethyl)benzene; α-(2-Nitro-3-trifluoromethylphenyl)methanol; (2-Nitro-α,α,α-trifluoro-m-tolyl)methanol; 3-(Trifluoromethyl)-2-nitrobenzenemethanol; m-Tolyl, 2-nitro-α,α,α-trifluoro-, carbinol
EINECS	Contact for details

Quality Control

Our (2-Nitro-3-(Trifluoromethyl)Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP (Current Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.