Description

6-Fluoro-5-Methoxy-3-Pyridinol is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents, provides valuable electronic and steric properties for modulating the activity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom improves metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Fluoro-5-Methoxy-3-Pyridinol
CAS No.	1227511-69-4
Molecular Formula	C6H6FNO2
Molecular Weight	143.12 g/mol
Synonyms	3-Pyridinol, 6-fluoro-5-methoxy-; 5-Methoxy-6-fluoropyridin-3-ol; 6-Fluoro-5-methoxypyridin-3-ol; 6-Fluoro-5-methoxy-3-hydroxypyridine; 3-Hydroxy-6-fluoro-5-methoxypyridine; 6-Fluoro-5-methoxy-3-pyridol; 6-F-5-MeO-3-Pyridinol
EINECS	Contact for details

Quality Control

Our 6-Fluoro-5-Methoxy-3-Pyridinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.