Description

(3-Bromo-2-Chloropyridin-4-Yl)Methanol is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily utilized by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functional complexity into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and material science.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying biological pathways and target engagement.
• Functional Material Research: Acts as a monomer or modifier in the synthesis of advanced polymers and electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	(3-Bromo-2-Chloropyridin-4-Yl)Methanol
CAS No.	1227502-15-9
Molecular Formula	C6H5BrClNO
Molecular Weight	222.47 g/mol
Synonyms	4-(Hydroxymethyl)-3-bromo-2-chloropyridine; 3-Bromo-2-chloro-4-pyridinemethanol; 2-Chloro-3-bromo-4-pyridinemethanol; (3-Bromo-2-chloro-4-pyridinyl)methanol; 4-Pyridinemethanol, 3-bromo-2-chloro-; (3-Bromo-2-chloro-pyridin-4-yl)-methanol
EINECS	Contact for details

Quality Control

Every batch of (3-Bromo-2-Chloropyridin-4-Yl)Methanol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our products are developed to meet the stringent requirements of cGMP and ICH Q7 guidelines for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.