Description

2-Chloro-4-Methoxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique molecular structure, featuring both chloro and trifluoromethyl substituents, provides exceptional reactivity and stability for creating complex target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis & Contract Manufacturing: Employed by fine chemical companies for bespoke synthesis projects requiring specific halogenated pyridine scaffolds.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-4-Methoxy-5-(Trifluoromethyl)Pyridine
CAS No.	1227499-99-1
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	5-(Trifluoromethyl)-2-chloro-4-methoxypyridine; 2-Chloro-4-methoxy-5-(trifluoromethyl)pyridine; 4-Methoxy-2-chloro-5-trifluoromethylpyridine; 2-Chloro-4-methoxy-5-trifluoromethylpyridine; 2-Chloro-4-methoxy-5-(trifluoromethyl)pyridine (CAS 1227499-99-1); Pyridine, 2-chloro-4-methoxy-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Methoxy-5-(Trifluoromethyl)Pyridine is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.