Description

6-Bromo-3-Methoxy-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for medicinal chemistry and agrochemical research, enabling the rapid synthesis of complex molecules for screening and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the pyridine core and halogen substituent.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-Bromo-3-Methoxy-2-(Trifluoromethyl)Pyridine
CAS No.	1227499-22-0
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	2-(Trifluoromethyl)-6-bromo-3-methoxypyridine; 3-Methoxy-2-(trifluoromethyl)-6-bromopyridine; 6-Bromo-3-methoxy-2-trifluoromethylpyridine; 2-Bromo-5-methoxy-6-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-3-Methoxy-2-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for critical R&D and scale-up activities. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (NMR/IR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.