Description

1-(Phenylsulfonyl)-4,6-Dichloro-2-Methyl-7-Azaindole is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in modern pharmaceutical research and development, particularly in the synthesis of kinase inhibitors and other targeted therapeutic agents. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for complex molecule synthesis. The compound is supplied with full analytical documentation to ensure batch-to-batch consistency and support regulatory filings.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile azaindole scaffold.
• Process Chemistry: Serves as a critical intermediate in the scale-up and commercial route development for active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a tool compound or precursor in biochemical assays to study enzyme function and inhibition.
• Custom Synthesis: A starting material for the preparation of more complex, functionalized azaindole derivatives for specialized applications.

Basic Information

Product Name	1-(Phenylsulfonyl)-4,6-Dichloro-2-Methyl-7-Azaindole
CAS No.	1227268-69-0
Molecular Formula	C15H10Cl2N2O2S
Molecular Weight	353.22 g/mol
Synonyms	4,6-Dichloro-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 4,6-Dichloro-2-methyl-1-(phenylsulfonyl)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4,6-dichloro-2-methyl-1-(phenylsulfonyl)-; 1-Benzenesulfonyl-4,6-dichloro-2-methyl-7-azaindole; 4,6-Dichloro-2-methyl-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-4,6-Dichloro-2-Methyl-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with customer specifications for pharmaceutical R&D use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.