Description

3-Cyclopropyl-2-Fluoropyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, combining a cyclopropyl ring with a fluorine atom on the pyridine core, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluoropyridine moiety can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science: Employed in the synthesis of advanced organic electronic materials, such as charge-transport layers or fluorinated polymers with specific optoelectronic properties.
• Chemical Biology Probe: Useful for incorporating fluorine atoms into bioactive molecules as isotopic labels or to modulate lipophilicity and metabolic stability in probe design.

Basic Information

Product Name	3-Cyclopropyl-2-Fluoropyridine
CAS No.	1227177-68-5
Molecular Formula	C8H8FN
Molecular Weight	137.15 g/mol
Synonyms	2-Fluoro-3-cyclopropylpyridine; 3-Cyclopropyl-2-fluoropyridine; 2-Fluoro-3-cyclopropyl-pyridine; Pyridine, 3-cyclopropyl-2-fluoro-; 1227177-68-5
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-2-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.