Description

2-Amino-5-Iodo-Nicotinic Acid Methyl Ester is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both an amino and an iodo substituent, makes it a critical building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides due to its bioactive pyridine core.
• Material Science: Building block for creating specialized ligands, catalysts, and organic electronic materials.
• Chemical Synthesis: Serves as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex functionalities.
• Life Science Research: Utilized in biochemical research as a probe or tracer molecule in diagnostic assay development.

Basic Information

Product Name	2-Amino-5-Iodo-Nicotinic Acid Methyl Ester
CAS No.	1227048-78-3
Molecular Formula	C7H7IN2O2
Molecular Weight	278.05 g/mol
Synonyms	Methyl 2-Amino-5-iodonicotinate; 5-Iodo-2-aminonicotinic Acid Methyl Ester; 2-Amino-5-iodopyridine-3-carboxylic Acid Methyl Ester; 3-Pyridinecarboxylic acid, 2-amino-5-iodo-, methyl ester; Methyl 2-amino-5-iodo-3-pyridinecarboxylate; 2-Amino-5-iodo-3-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Iodo-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.