Description

5-Ethoxy-1H-Pyrazolo[4,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, central nervous system (CNS), and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Serves as a scaffold for developing new herbicides and pesticides with specific modes of action.
• Material Science: Used in the research and development of organic electronic materials and photoactive compounds.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assay development and target identification.

Basic Information

Product Name	5-Ethoxy-1H-Pyrazolo[4,3-B]Pyridine
CAS No.	1226903-85-0
Molecular Formula	C9H9N3O
Molecular Weight	175.19 g/mol
Synonyms	5-Ethoxy-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine, 5-ethoxy-; 5-Ethoxy-1H-pyrazolo[4,3-b]pyridine; 5-Ethoxypyrazolo[4,3-b]pyridine; 1226903-85-0; Ethoxy-pyrazolopyridine; 5-Ethoxy-pyrazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Ethoxy-1H-Pyrazolo[4,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.