Description

3-Bromo-2-(Methylthio)-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block. This compound is specifically engineered for advanced synthesis, offering a unique combination of bromine, methylthio, and trifluoromethyl substituents on the pyridine ring, which are critical for modulating the electronic and steric properties of target molecules. It is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including kinase inhibitors and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a versatile building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2-(Methylthio)-5-(Trifluoromethyl)Pyridine
CAS No.	1226808-64-5
Molecular Formula	C8H5BrF3NS
Molecular Weight	272.10 g/mol
Synonyms	3-Bromo-2-(methylthio)-5-(trifluoromethyl)pyridine; 2-Methylsulfanyl-3-bromo-5-trifluoromethylpyridine; 5-(Trifluoromethyl)-3-bromo-2-(methylthio)pyridine; Pyridine, 3-bromo-2-(methylthio)-5-(trifluoromethyl)-; 3-Bromo-2-methylsulfanyl-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(Methylthio)-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.