Description

4-Chloro-2-Difluoromethyl-6-Methyl-Pyridine is a high-value, multi-functional pyridine derivative characterized by its unique halogenated and fluorinated structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex agrochemicals and specialty chemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and crop protection industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the difluoromethyl group for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of novel fluorinated polymers and liquid crystals, where the fluorine atoms impart desirable properties like chemical resistance and thermal stability.
• Custom Synthesis and Contract Manufacturing: A pivotal starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-2-Difluoromethyl-6-Methyl-Pyridine
CAS No.	1226800-12-9
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	4-Chloro-2-(difluoromethyl)-6-methylpyridine; 2-(Difluoromethyl)-4-chloro-6-methylpyridine; 6-Methyl-4-chloro-2-difluoromethylpyridine; 1226800-12-9; 4-Chloro-2-difluoromethyl-6-methylpyridine; Pyridine, 4-chloro-2-(difluoromethyl)-6-methyl-
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Difluoromethyl-6-Methyl-Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent composition. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. Keep container tightly sealed to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.